In responding to an inquiry by the Pharisees as to whether it was lawful for a man to divorce his wife for any and every reason (Matt. 19: 1-4), Jesus pointed to Genesis 2:24 in stating that:
Haven’t you read,’ he replied, ‘that at the beginning the Creator “made them male and female,” and said, “For this reason a man will leave his father and mother and be united to his wife, and the two will become one flesh”? So they are no longer two, but one flesh. Therefore, what God has joined together, let no one separate. (Matt. 19:4-6, NIV)